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Grade AproductionSource date Jun 25, 2025· Last verified Oct 17, 2026

Did an AI voice agent increase colorectal cancer screening sign-ups?

WellSpan Health · Hospitals & Health Systems

Header image: A group of doctors and nurses standing together in a hallway

WellSpan Health used 'Ana', a multilingual AI care agent from Hippocratic AI, to phone 1,878 patients due for colorectal cancer screening in September 2024. A peer-reviewed JMIR study found FIT-kit opt-in of 18.2% among Spanish-speaking patients vs 7.1% among English-speaking patients; the study was funded by Hippocratic AI.

Reported outcomes

FIT test opt-in (Spanish vs English speakers)
18.2% vs 7.1%
Source [1] · independently reported
connect rate (Spanish vs English speakers)
69.6% vs 53.0%
Source [1] · independently reported

Outcomes are reported exactly as stated by the source; we have not independently audited them.

How it works

  1. Eligible patients without active web-based health profiles are selected for outreach.
  2. The AI agent calls each patient in their preferred language.
  3. It explains colorectal cancer screening and answers questions.
  4. Patients who opt in get a FIT kit mailed to their home.

Risks & compliance

  • Patient-facing clinical conversation; escalation path required
  • Study outcome is opt-in, not completed screening

Healthcare cases cover operational and commercial workflows. Nothing here is medical advice or a claim about a device's or drug's efficacy.

Editor's notes

  • JMIR conflict-of-interest statement: most authors are Hippocratic AI employees and Hippocratic AI funded the study; WellSpan provided data.
  • The vendor page reports an 89% Spanish-speaker connect rate; the peer-reviewed paper reports 69.6%. We use the paper's figure.
  • Paper text verified via Europe PMC (PMC12278996) because jmir.org blocks automated fetches.
Build this yourself

Tools mentioned & how to build it

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Tools mentioned

  • Hippocratic AI (Hippocratic AI)
    Healthcare AI agents for non-diagnostic patient outreach.

Build a version yourself

  • Retell AI
    Build and deploy phone agents for scheduling, intake and call routing.
  • Make
    Visual no-code automation with AI agents; good for intake, routing and follow-up flows.
  • ElevenLabs
    Voice models and a conversational-agent platform behind many voice agents.

All tools by category →

Sources

[1]Journal of Medical Internet Research· peer reviewed paper· Jun 25, 2025independent
“Spanish-speaking patients demonstrated significantly higher engagement across all measures than English-speaking patients with respect to FIT test opt-in rates (18.2% vs 7.1%, P<.001)”
Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective Analysis
[2]Hippocratic AI· vendor customer story· Oct 24, 2024
“Our AI agent, named Ana, is designed to conduct targeted outreach to at-risk patients, with a particular focus on Spanish-speaking populations.”
Colorectal Cancer Screening AI Case Study

Grade rationale: Named organization, quantified outcome, peer-reviewed paper (note vendor funding and authorship). Automated check on Oct 17, 2026: 2/2 quotes and 2/2 outcome claims matched the source. Compiled by the Agent Casefile research desk (AI-assisted; see methodology). Spot an error? Request a correction.

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