{
  "id": "uc_2026_000014",
  "slug": "wellspan-hippocratic-ana-colorectal-screening-outreach",
  "title": "Did an AI voice agent increase colorectal cancer screening sign-ups?",
  "answer": "WellSpan Health used 'Ana', a multilingual AI care agent from Hippocratic AI, to phone 1,878 patients due for colorectal cancer screening in September 2024. A peer-reviewed JMIR study found FIT-kit opt-in of 18.2% among Spanish-speaking patients vs 7.1% among English-speaking patients; the study was funded by Hippocratic AI.",
  "industry": "healthcare-providers",
  "sub_industry": "Integrated health system",
  "roles": [
    "patient-access",
    "clinical-ops"
  ],
  "function": "clinical",
  "tasks": [
    "outbound-patient-calls",
    "screening-outreach",
    "test-kit-ordering"
  ],
  "agent_pattern": "voice-agent",
  "autonomy_level": 3,
  "tools": [
    {
      "name": "Hippocratic AI care agent ('Ana')",
      "vendor": "Hippocratic AI",
      "url": "https://hippocraticai.com/",
      "affiliate": false
    }
  ],
  "integrations": [
    "patient lists from EHR",
    "FIT kit mail-out"
  ],
  "deployment_status": "production",
  "organization": {
    "name": "WellSpan Health",
    "type": "health system",
    "named": true
  },
  "outcomes": [
    {
      "metric": "FIT test opt-in (Spanish vs English speakers)",
      "value": "18.2% vs 7.1%",
      "source_ref": 1,
      "self_reported": false
    },
    {
      "metric": "connect rate (Spanish vs English speakers)",
      "value": "69.6% vs 53.0%",
      "source_ref": 1,
      "self_reported": false
    }
  ],
  "evidence_grade": "A",
  "grade_rationale": "Named organization, quantified outcome, peer-reviewed paper (note vendor funding and authorship).",
  "sources": [
    {
      "ref": 1,
      "url": "https://www.jmir.org/2025/1/e71211",
      "publisher": "Journal of Medical Internet Research",
      "title": "Using a Multilingual AI Care Agent to Reduce Disparities in Colorectal Cancer Screening for Higher Fecal Immunochemical Test Adoption Among Spanish-Speaking Patients: Retrospective Analysis",
      "published": "2025-06-25",
      "type": "peer-reviewed-paper",
      "quote": "Spanish-speaking patients demonstrated significantly higher engagement across all measures than English-speaking patients with respect to FIT test opt-in rates (18.2% vs 7.1%, P<.001)",
      "independent": true,
      "accessed": "2026-10-17"
    },
    {
      "ref": 2,
      "url": "https://hippocraticai.com/colorectal-cancer-case-study/",
      "publisher": "Hippocratic AI",
      "title": "Colorectal Cancer Screening AI Case Study",
      "published": "2024-10-24",
      "type": "vendor-customer-story",
      "quote": "Our AI agent, named Ana, is designed to conduct targeted outreach to at-risk patients, with a particular focus on Spanish-speaking populations.",
      "independent": false,
      "accessed": "2026-10-17"
    }
  ],
  "how_it_works": [
    "Eligible patients without active web-based health profiles are selected for outreach.",
    "The AI agent calls each patient in their preferred language.",
    "It explains colorectal cancer screening and answers questions.",
    "Patients who opt in get a FIT kit mailed to their home."
  ],
  "risks_compliance": [
    "Patient-facing clinical conversation; escalation path required",
    "Study outcome is opt-in, not completed screening"
  ],
  "notes": [
    "JMIR conflict-of-interest statement: most authors are Hippocratic AI employees and Hippocratic AI funded the study; WellSpan provided data.",
    "The vendor page reports an 89% Spanish-speaker connect rate; the peer-reviewed paper reports 69.6%. We use the paper's figure.",
    "Paper text verified via Europe PMC (PMC12278996) because jmir.org blocks automated fetches."
  ],
  "models": [],
  "medtech_relevance": null,
  "related": [],
  "first_seen": "2026-10-17",
  "last_verified": "2026-10-17",
  "sponsored": false,
  "license": "CC BY 4.0 (summary text); quotes and sources belong to their owners",
  "verification": {
    "checked": "2026-10-17",
    "checker": "pipeline.verify (quote match + outcome-number match)",
    "methods": [
      "auto:fetch",
      "auto:mirror"
    ],
    "quotes_matched": 2,
    "quotes_total": 2,
    "claims_matched": 2,
    "claims_total": 2,
    "passed": true
  },
  "url": "https://agentcasefile.com/cases/wellspan-hippocratic-ana-colorectal-screening-outreach/",
  "industry_label": "Hospitals & Health Systems",
  "role_labels": [
    "Patient Access & Outreach",
    "Clinicians & Clinical Ops"
  ],
  "vertical": "healthcare"
}